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What is Trexall used for? Trexall (methotrexate) is an antimetabolite drug that is used to treat some cancers, severe skin diseases such as severe psoriasis, and to treat forms of rheumatoid arthritis. Trexall is available in generic form as methotrexate.
How bad is methotrexate for you? Methotrexate may cause very serious, life-threatening side effects. You should only take methotrexate to treat cancer or certain other conditions that are very severe and that cannot be treated with other medications. Methotrexate may cause liver damage, especially when it is taken for a long period of time.
What happens if you take methotrexate and folic acid on the same day? It is considered that the folic acid dose should be high enough to prevent folate deficiency. They state that folic acid can be given any day as long as it is not on the same day as methotrexate. Folic acid reduces toxic effects and improves continuation of therapy and compliance.
